PE Anti-Human CD326/EpCAM Antibody[9C4]
Cat No.: FCE3056
Size：
| Product Name: | PE Anti-Human CD326/EpCAM Antibody[9C4] |
| Cat No.: | FCE3056 |
| host: | Mouse |
| uniprot id: | P16422 |
| geneid: | 4072 |
| application: | FCM |
| isotype: | Mouse IgG2b, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD326/EpCAM |
| conjugation: | PE |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | 9C4 |
| background: | CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas. |
| target synonym: | EpCAM;Ep-CAM;GA733-2;M1S2;M4S1;MIC18;TACSTD1; TROP1; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | Human colon carcinoma cell line HT29 are stained with PE Anti-Human CD326 Antibody (filled gray histogram). Unstained Human colon carcinoma cell line HT29 (empty black histogram) are used as control. |