APC Anti-Human CD206/MMR Antibody[15-2]
Cat No.: FCE3052
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| Product Name: | APC Anti-Human CD206/MMR Antibody[15-2] |
| Cat No.: | FCE3052 |
| host: | Mouse |
| uniprot id: | P22897 |
| geneid: | 4360 |
| application: | FCM |
| isotype: | Mouse IgG1, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD206/MMR |
| conjugation: | APC |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | 15-2 |
| background: | Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity. |
| target synonym: | CLEC13D;CLEC13DL;MRC1L1;MMR;hMR; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Human CD206 gene are stained with APC Anti-Human CD206 Antibody (filled gray histogram) or APC Mouse IgG1, κ Isotype Control (empty black histogram). |
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