APC Anti-Human CD184/CXCR4 Antibody[12G5]
Cat No.: FCE3030
Size:
Product Name: | APC Anti-Human CD184/CXCR4 Antibody[12G5] |
Cat No.: | FCE3030 |
host: | Mouse |
uniprot id: | P61073 |
geneid: | 7852 |
application: | FCM |
isotype: | Mouse IgG2a, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD184 |
conjugation: | APC |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | 12G5 |
background: | CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2. |
target synonym: | FB22;Fusin;HM89;LCR1;LAP-3; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | Human peripheral blood lymphocytes are stained with APC Anti-Human CD184/CXCR4 Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |