APC Anti-Human CD161 Antibody[HP-3G10]
Cat No.: FCE3018
Size:
Product Name: | APC Anti-Human CD161 Antibody[HP-3G10] |
Cat No.: | FCE3018 |
host: | Mouse |
uniprot id: | Q12918 |
geneid: | 3820 |
application: | FCM |
isotype: | Mouse IgG1, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD161 |
conjugation: | APC |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | HP-3G10 |
background: | CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161. |
target synonym: | CLEC5B; NKRP1A;NKR-P1A;HNKR-P1a;KLRB1; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | Human peripheral blood lymphocytes are stained with APC Anti-Human CD161 Antibody and FITC Anti-Human CD4 Antibody. |