APC Anti-Human CD69 Antibody[FN50]
Cat No.: FCE2893
Size:
Product Name: | APC Anti-Human CD69 Antibody[FN50] |
Cat No.: | FCE2893 |
host: | Mouse |
uniprot id: | Q07108 |
geneid: | 969 |
application: | FCM |
isotype: | Mouse IgG1, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD69 |
conjugation: | APC |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | FN50 |
background: | CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells. |
target synonym: | Early activation antigen CD69;Activation inducer molecule;AIM;EA1;MLR-3; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | PMA and ionomycin-stimulated (4h) Jurkat cells are stained with APC Anti-Human CD69 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control APC (empty black histogram). |