APC Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Cat No.: FCE2807
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| Product Name: | APC Anti-Mouse CD279/PD-1 Antibody[29F.1A12] |
| Cat No.: | FCE2807 |
| host: | Rat |
| uniprot id: | Q02242 |
| geneid: | 18566 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD279/PD-1 |
| conjugation: | APC |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | 29F.1A12 |
| background: | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
| target synonym: | PD-1; Programmed Death-1; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | Con-A stimulated C57BL/6 splenocytes (3 days) are stained with APC Anti-Mouse CD279/PD-1 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |