PE/Cyanine5 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
Cat No.: FCE2605
Size：
| Product Name: | PE/Cyanine5 Anti-Mouse CD49b/pan-NK cells Antibody[DX5] |
| Cat No.: | FCE2605 |
| host: | Rat |
| uniprot id: | Q62469 |
| geneid: | 16398 |
| application: | FCM |
| isotype: | Rat IgM, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD49b/pan-NK cells |
| conjugation: | PE/Cyanine5 |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | DX5 |
| background: | DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen. |
| target synonym: | Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine bone marrow cells are stained with PE/Cyanine5 Anti-Mouse CD49b Antibody (filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control. |