PE Anti-Mouse CD119 Antibody[GR-20]
Cat No.: FCE2598
Size：
| Product Name: | PE Anti-Mouse CD119 Antibody[GR-20] |
| Cat No.: | FCE2598 |
| host: | Rat |
| uniprot id: | P15261 |
| geneid: | 15979 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD119 |
| conjugation: | PE |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | GR-20 |
| background: | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
| target synonym: | Interferon gamma receptor 1;Ifngr1;IFN-gamma-R1;IFN-gamma-R-alpha;CD119; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | Raw264.7 cells are stained with PE Anti-Mouse CD119 Antibody (filled gray histogram) or PE Rat IgG2a, κ Isotype Control (empty black histogram). |