PerCP Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]
Cat No.: FCE2538
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| Product Name: | PerCP Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] |
| Cat No.: | FCE2538 |
| host: | Rat |
| uniprot id: | |
| geneid: | 19264,5788 |
| application: | FCM |
| isotype: | Rat IgM, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD45R/B220 |
| conjugation: | PerCP |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | RA3.3A 1/6.1 |
| background: | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| target synonym: | B220; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine splenocytes are stained with PerCP Anti-Mouse CD45R/B220 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |
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