PE Anti-Mouse CD117/c-Kit Antibody[2B8]
Cat No.: FCE2224
Size：
| Product Name: | PE Anti-Mouse CD117/c-Kit Antibody[2B8] |
| Cat No.: | FCE2224 |
| host: | Rat |
| uniprot id: | P05532 |
| geneid: | 16590 |
| application: | FCM |
| isotype: | Rat IgG2b, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD117/c-Kit |
| conjugation: | PE |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | 2B8 |
| background: | CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells. |
| target synonym: | Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine bone marrow cells are stained with Fluor® 647 Anti-Mouse CD45R/B220 Antibody and PE Anti-Mouse CD117 Antibody (Left). Bone marrow cells are stained with Fluor® 647 Anti-Mouse CD45R/B220 Antibody and PE Rat IgG2b, κ Isotype Control (Right). |