PE Fluor® 594 Anti-Mouse/Human CD11b Antibody[M1/70]
Cat No.: FCE2115
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| Product Name: | PE Fluor® 594 Anti-Mouse/Human CD11b Antibody[M1/70] |
| Cat No.: | FCE2115 |
| host: | Rat |
| uniprot id: | P05555;P11215; |
| geneid: | 16409,3684 |
| application: | FCM |
| isotype: | Rat IgG2b, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD11b |
| conjugation: | PE/ Fluor® 594 |
| species reactivity: | Human,Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | M1/70 |
| background: | CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. |
| target synonym: | Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine bone marrow cells are stained with Fluor® Red 780 Anti-Mouse CD45R/B220 Antibody and PE/ Fluor® 594 Anti-Mouse/Human CD11b Antibody (Left). Bone marrow cells are stained with Fluor® Red 780 Anti-Mouse CD45R/B220 Antibody and PE/ Fluor® 594 Rat IgG2b, κ Isotype Control (Right). |
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