PE Anti-Human CD54 Antibody[15.2]
Cat No.: FCE1857
Size:
Product Name: | PE Anti-Human CD54 Antibody[15.2] |
Cat No.: | FCE1857 |
host: | Mouse |
uniprot id: | P05362 |
geneid: | 3383 |
application: | FCM |
isotype: | Mouse IgG1, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD54 |
conjugation: | PE |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | 15.2 |
background: | CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen. |
target synonym: | Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | Human peripheral blood lymphocytes are stained with PE Anti-Human CD54 Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |