Fluor® 488 Anti-Mouse CD122/IL-2RB Antibody[5H4]
Cat No.: FCE1746
Size：
| Product Name: | Fluor® 488 Anti-Mouse CD122/IL-2RB Antibody[5H4] |
| Cat No.: | FCE1746 |
| host: | Rat |
| uniprot id: | P16297 |
| geneid: | 16185 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD122/IL-2RB |
| conjugation: | Fluor® 488 |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | 5H4 |
| background: | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| target synonym: | Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine splenocytes are stained with Fluor® 488 Anti-Mouse CD122 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |
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