PE Fluor® 594 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Cat No.: FCE1736
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| Product Name: | PE Fluor® 594 Anti-Mouse CD40 Antibody[FGK4.5/FGK45] |
| Cat No.: | FCE1736 |
| host: | Rat |
| uniprot id: | P27512 |
| geneid: | 21939 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD40 |
| conjugation: | PE/ Fluor® 594 |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | FGK4.5/FGK45 |
| background: | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
| target synonym: | Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD19 Antibody and PE/ Fluor® 594 Anti-Mouse CD40 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD19 Antibody and PE/ Fluor® 594 Rat IgG2a, κ Isotype Control (Right). |
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