PE/Cyanine5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Cat No.: FCE1720
Size:
Product Name: | PE/Cyanine5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45] |
Cat No.: | FCE1720 |
host: | Rat |
uniprot id: | P27512 |
geneid: | 21939 |
application: | FCM |
isotype: | Rat IgG2a, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD40 |
conjugation: | PE/Cyanine5 |
species reactivity: | Mouse |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | FGK4.5/FGK45 |
background: | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
target synonym: | Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | C57BL/6 murine splenocytes are stained with PE/Cyanine5 Anti-Mouse CD40 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |