AF/LE Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Cat No.: FCE1714
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| Product Name: | AF/LE Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45] |
| Cat No.: | FCE1714 |
| host: | Rat |
| uniprot id: | P27512 |
| geneid: | 21939 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD40 |
| conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| clone no.: | FGK4.5/FGK45 |
| background: | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
| target synonym: | Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5; |
| concentration: | 0.5 mg/mL |
| buffer: | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
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