PE Anti-Mouse CD127/IL-7RA Antibody[A7R34]
Cat No.: FCE1686
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| Product Name: | PE Anti-Mouse CD127/IL-7RA Antibody[A7R34] |
| Cat No.: | FCE1686 |
| host: | Rat |
| uniprot id: | P16872 |
| geneid: | 16197 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD127 |
| conjugation: | PE |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | A7R34 |
| background: | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. |
| target synonym: | Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD3 Antibody and PE Anti-Mouse CD127/IL-7RA Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD3 Antibody and PE Rat IgG2a, κ Isotype Control (Right). |
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