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Myc Tag Rabbit pAb

Cat No.: ATL1038
Size:
Product Name: Myc Tag Rabbit pAb
Cat No.: ATL1038
source: Rabbit
reactivity: Other
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:20
format: Liquid
immunogen: A synthetic peptide of Myc tag
calculated molecular weight: 49 kDa
observed molecular weight: According to the fused protein
genbank accession number: P01106
gene id (ncbi):
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MRTL; MYCC; c-Myc; bHLHe39
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]