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eIF4E Recombinant Rabbit mAb

Cat No.: ARM1766
Size:
Product Name: eIF4E Recombinant Rabbit mAb
Cat No.: ARM1766
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human eIF4E
calculated molecular weight: 25 kDa
observed molecular weight: 25 kDa
genbank accession number: P06730
gene id (ncbi): 1977
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5-- end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5---cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]