XPD Recombinant Rabbit mAb
Cat No.: ARM1740
Size：
| Product Name: | XPD Recombinant Rabbit mAb |
| Cat No.: | ARM1740 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human XPD |
| calculated molecular weight: | 87 kDa |
| observed molecular weight: | 80 kDa |
| genbank accession number: | P18074 |
| gene id (ncbi): | 2068 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | EM9; TTD; XPD; TTD1; COFS2; TFIIH |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |