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ALDH7A1 Recombinant Rabbit mAb

Cat No.: ARM1685
Size:
Product Name: ALDH7A1 Recombinant Rabbit mAb
Cat No.: ARM1685
source: Rabbit
reactivity: Human, Mouse
applications: WB,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human ALDH7A1
calculated molecular weight: 59 kDa
observed molecular weight: 59 kDa
genbank accession number: P49419
gene id (ncbi): 501
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: EPD; PDE; ATQ1
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]