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NEDD4 Recombinant Rabbit mAb

Cat No.: ARM1564
Size:
Product Name: NEDD4 Recombinant Rabbit mAb
Cat No.: ARM1564
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC,IP
clonality: Monoclonal
recommended dilution: WB,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human NEDD4
calculated molecular weight: 149 kDa
observed molecular weight: 115 kDa
genbank accession number: P46934
gene id (ncbi): 4734
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: RPF1; NEDD4-1
category: Primary Ab
concentration: 1mg/ml
background: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]