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KIAA1967 Recombinant Rabbit mAb

Cat No.: ARM1467
Size:
Product Name: KIAA1967 Recombinant Rabbit mAb
Cat No.: ARM1467
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human KIAA1967
calculated molecular weight: 103 kDa
observed molecular weight: 130 kDa
genbank accession number: Q8N163
gene id (ncbi): 57805
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967
category: Primary Ab
concentration: 1mg/ml
background: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis.