KIAA1967 Recombinant Rabbit mAb
Cat No.: ARM1467
| Product Name: | KIAA1967 Recombinant Rabbit mAb |
| Cat No.: | ARM1467 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF,FC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,FC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human KIAA1967 |
| calculated molecular weight: | 103 kDa |
| observed molecular weight: | 130 kDa |
| genbank accession number: | Q8N163 |
| gene id (ncbi): | 57805 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. |
