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Pumilio 1 Recombinant Rabbit mAb

Cat No.: ARM1451
Size:
Product Name: Pumilio 1 Recombinant Rabbit mAb
Cat No.: ARM1451
source: Rabbit
reactivity: Human, Mouse
applications: WB,IHC,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Pumilio 1
calculated molecular weight: 127 kDa
observed molecular weight: 140 kDa
genbank accession number: Q14671
gene id (ncbi): 9698
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PUMH; HSPUM; PUMH1; PUML1
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3-- untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]