AMPK alpha 1/2 Recombinant Rabbit mAb
Cat No.: ARM1434
Size：
| Product Name: | AMPK alpha 1/2 Recombinant Rabbit mAb |
| Cat No.: | ARM1434 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human AMPK alpha 2 |
| calculated molecular weight: | 64,62 kDa |
| observed molecular weight: | 62 kDa |
| genbank accession number: | P54646 |
| gene id (ncbi): | 5563 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | AMPK; AMPK2; PRKAA; AMPKa2 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008] |