Caspase-10 Recombinant Rabbit mAb
Cat No.: ARM1420
Size：
| Product Name: | Caspase-10 Recombinant Rabbit mAb |
| Cat No.: | ARM1420 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,FC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,FC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Caspase-10 |
| calculated molecular weight: | 59 kDa |
| observed molecular weight: | 59 kDa |
| genbank accession number: | Q92851 |
| gene id (ncbi): | 843 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MCH4; ALPS2; FLICE2 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011] |