Caspase-11 Recombinant Rabbit mAb
Cat No.: ARM1292
Size：
| Product Name: | Caspase-11 Recombinant Rabbit mAb |
| Cat No.: | ARM1292 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Caspase-11 |
| calculated molecular weight: | 43 kDa |
| observed molecular weight: | 43,38,25 kDa |
| genbank accession number: | P70343 |
| gene id (ncbi): | 12363 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Caspl; ich-3; CASP-4; Casp11; CASP-11 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015] |