KDM4B/JMJD2B Recombinant Rabbit mAb
Cat No.: ARM1266
| Product Name: | KDM4B/JMJD2B Recombinant Rabbit mAb |
| Cat No.: | ARM1266 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human KDM4B/JMJD2B |
| calculated molecular weight: | 122 kDa |
| observed molecular weight: | 150 kDa |
| genbank accession number: | O94953 |
| gene id (ncbi): | 23030 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | JMJD2B; TDRD14B |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Histone demethylase that specifically demethylates --Lys-9-- of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 --Lys-4--, H3 --Lys-27--, H3 --Lys-36-- nor H4 --Lys-20--. Only able to demethylate trimethylated H3 --Lys-9--, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. |
