NFYA Recombinant Rabbit mAb
Cat No.: ARM1211
Size：
| Product Name: | NFYA Recombinant Rabbit mAb |
| Cat No.: | ARM1211 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,ICC/IF,FC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,ICC/IF,FC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human NFYA |
| calculated molecular weight: | 37 kDa |
| observed molecular weight: | 37 kDa |
| genbank accession number: | P23511 |
| gene id (ncbi): | 4800 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HAP2; CBF-A; CBF-B; NF-YA |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008] |