DNA Nucleotidylexotransferase Recombinant Rabbit mAb
Cat No.: ARM2911
Size:
Product Name: | DNA Nucleotidylexotransferase Recombinant Rabbit mAb |
Cat No.: | ARM2911 |
source: | Rabbit |
reactivity: | Human |
applications: | WB, IHC |
clonality: | Monoclonal |
recommended dilution: | WB, IHC |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human TdT |
calculated molecular weight: | 59 kDa |
observed molecular weight: | 59 kDa |
genbank accession number: | P04053 |
gene id (ncbi): | 1791 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | TDT |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3---hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] |