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Angiotensin II Type 1 Receptor Recombinant Rabbit mAb

Cat No.: ARM2901
Size:
Product Name: Angiotensin II Type 1 Receptor Recombinant Rabbit mAb
Cat No.: ARM2901
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Monoclonal
recommended dilution: WB
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Angiotensin II Type 1 Receptor
calculated molecular weight: 41 kDa
observed molecular weight: 41 kDa
genbank accession number: P30556
gene id (ncbi): 185
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B
category: Primary Ab
concentration: 1mg/ml
background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]