SHP2 Recombinant Rabbit mAb
Cat No.: ARM2898
Size:
Product Name: | SHP2 Recombinant Rabbit mAb |
Cat No.: | ARM2898 |
source: | Rabbit |
reactivity: | Human |
applications: | WB, IHC, ICC/IF, FC, IP |
clonality: | Monoclonal |
recommended dilution: | WB, IHC, ICC/IF, FC, IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human SHP2 |
calculated molecular weight: | 68 kDa |
observed molecular weight: | 68 kDa |
genbank accession number: | Q06124 |
gene id (ncbi): | 5781 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016] |