Bak Recombinant Rabbit mAb
Cat No.: ARM2856
Size:
Product Name: | Bak Recombinant Rabbit mAb |
Cat No.: | ARM2856 |
source: | Rabbit |
reactivity: | Human |
applications: | WB, IHC, ICC/IF, FC, IP |
clonality: | Monoclonal |
recommended dilution: | WB, IHC, ICC/IF, FC, IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Bak |
calculated molecular weight: | 23 kDa |
observed molecular weight: | 23 kDa |
genbank accession number: | Q16611 |
gene id (ncbi): | 578 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | BAK; CDN1; BCL2L7; BAK-LIKE |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008] |