Bak Recombinant Rabbit mAb
Cat No.: ARM2856
Size：
| Product Name: | Bak Recombinant Rabbit mAb |
| Cat No.: | ARM2856 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB, IHC, ICC/IF, FC, IP |
| clonality: | Monoclonal |
| recommended dilution: | WB, IHC, ICC/IF, FC, IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Bak |
| calculated molecular weight: | 23 kDa |
| observed molecular weight: | 23 kDa |
| genbank accession number: | Q16611 |
| gene id (ncbi): | 578 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | BAK; CDN1; BCL2L7; BAK-LIKE |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008] |