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Catalase Recombinant Rabbit mAb

Cat No.: ARM2848
Size:
Product Name: Catalase Recombinant Rabbit mAb
Cat No.: ARM2848
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, IHC
clonality: Monoclonal
recommended dilution: WB, IHC
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Catalase
calculated molecular weight: 60 kDa
observed molecular weight: 60 kDa
genbank accession number: P04040
gene id (ncbi): 847
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CAT
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer--s disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]