PON1 Recombinant Rabbit mAb
Cat No.: ARM2709
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Product Name: | PON1 Recombinant Rabbit mAb |
Cat No.: | ARM2709 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB, IP |
clonality: | Monoclonal |
recommended dilution: | WB, IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human PON1 |
calculated molecular weight: | 40 kDa |
observed molecular weight: | 40 kDa |
genbank accession number: | P27169 |
gene id (ncbi): | 5444 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ESA; PON; MVCD5 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017] |