ITCH Recombinant Rabbit mAb
Cat No.: ARM2337
Size：
| Product Name: | ITCH Recombinant Rabbit mAb |
| Cat No.: | ARM2337 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Monoclonal |
| recommended dilution: | WB |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ITCH/AIP4 |
| calculated molecular weight: | 103 kDa |
| observed molecular weight: | 103 kDa |
| genbank accession number: | Q96J02 |
| gene id (ncbi): | 83737 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | AIF4; AIP4; ADMFD; NAPP1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |