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Ku70 Recombinant Rabbit mAb

Cat No.: ARM2331
Size:
Product Name: Ku70 Recombinant Rabbit mAb
Cat No.: ARM2331
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Ku70
calculated molecular weight: 70 kDa
observed molecular weight: 70 kDa
genbank accession number: P12956
gene id (ncbi): 2547
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ML8; KU70; TLAA; CTC75; CTCBF; G22P1
category: Primary Ab
concentration: 1mg/ml
background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]