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IRF3 Recombinant Rabbit mAb

Cat No.: ARM2327
Size:
Product Name: IRF3 Recombinant Rabbit mAb
Cat No.: ARM2327
source: Rabbit
reactivity: Human
applications: WB,IHC,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IRF3
calculated molecular weight: 47 kDa
observed molecular weight: 47 kDa
genbank accession number: Q14653
gene id (ncbi): 3661
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IIAE7
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important in the innate immune response against DNA and RNA viruses. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2020]