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XRCC1 Recombinant Rabbit mAb

Cat No.: ARM2239
Size:
Product Name: XRCC1 Recombinant Rabbit mAb
Cat No.: ARM2239
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human XRCC1
calculated molecular weight: 70 kDa
observed molecular weight: 82 kDa
genbank accession number: P18887
gene id (ncbi): 7515
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: RCC; SCAR26
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]