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IGF1 Receptor Recombinant Rabbit mAb

Cat No.: ARM2195
Size:
Product Name: IGF1 Receptor Recombinant Rabbit mAb
Cat No.: ARM2195
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human IGF1 Receptor
calculated molecular weight: 155 kDa
observed molecular weight: 95 kDa
genbank accession number: P08069
gene id (ncbi): 3480
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IGFR; CD221; IGFIR; JTK13
category: Primary Ab
concentration: 1mg/ml
background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]