APC Recombinant Rabbit mAb
Cat No.: ARM2186
Size：
| Product Name: | APC Recombinant Rabbit mAb |
| Cat No.: | ARM2186 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,IHC,ICC/IF,FC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,FC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human APC |
| calculated molecular weight: | 312 kDa |
| observed molecular weight: | 160 kDa |
| genbank accession number: | P25054 |
| gene id (ncbi): | 324 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019] |