Nicotinic Acetylcholine Receptor alpha 4 Recombinant Rabbit mAb
Cat No.: ARM2167
Size：
| Product Name: | Nicotinic Acetylcholine Receptor alpha 4 Recombinant Rabbit mAb |
| Cat No.: | ARM2167 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,ICC/IF,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,ICC/IF,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 |
| calculated molecular weight: | 70 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | P43681 |
| gene id (ncbi): | 1137 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |