APLP2 Recombinant Rabbit mAb
Cat No.: ARM2153
Size：
| Product Name: | APLP2 Recombinant Rabbit mAb |
| Cat No.: | ARM2153 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human APLP2 |
| calculated molecular weight: | 87 kDa |
| observed molecular weight: | 115 kDa |
| genbank accession number: | Q06481 |
| gene id (ncbi): | 334 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | APPH; APPL2; CDEBP; APLP-2 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer--s disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |