SF3B1 Recombinant Rabbit mAb
Cat No.: ARM2131
Size：
| Product Name: | SF3B1 Recombinant Rabbit mAb |
| Cat No.: | ARM2131 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human SF3B1 |
| calculated molecular weight: | 146 kDa |
| observed molecular weight: | 155 kDa |
| genbank accession number: | O75533 |
| gene id (ncbi): | 23451 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron--s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |