CREB Regulated Transcription Coactivator 2 Recombinant Rabbit mAb
Cat No.: ARM2097
Size：
| Product Name: | CREB Regulated Transcription Coactivator 2 Recombinant Rabbit mAb |
| Cat No.: | ARM2097 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Monoclonal |
| recommended dilution: | WB |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human TORC2 |
| calculated molecular weight: | 73 kDa |
| observed molecular weight: | 80 kDa |
| genbank accession number: | Q53ET0 |
| gene id (ncbi): | 200186 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TORC2; TORC-2 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010] |