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AP3M1 Recombinant Rabbit mAb

Cat No.: ARM2087
Size:
Product Name: AP3M1 Recombinant Rabbit mAb
Cat No.: ARM2087
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC
clonality: Monoclonal
recommended dilution: WB,ICC/IF,FC
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human AP3M1
calculated molecular weight: 47 kDa
observed molecular weight: 47 kDa
genbank accession number: Q9Y2T2
gene id (ncbi): 26985
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AP-3 adaptor complex mu3A subunit; Mu-adaptin 3A; Mu3A-adaptin
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]