Acetyl Coenzyme A Carboxylase Recombinant Rabbit mAb
Cat No.: ARM2074
Size：
| Product Name: | Acetyl Coenzyme A Carboxylase Recombinant Rabbit mAb |
| Cat No.: | ARM2074 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Acetyl Coenzyme A Carboxylase |
| calculated molecular weight: | 277 kDa |
| observed molecular weight: | 277 kDa |
| genbank accession number: | O00763 |
| gene id (ncbi): | 31 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ACC; ACAC; ACC1; ACCA; ACACAD |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5-- sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |