NDUFA1 Recombinant Rabbit mAb
Cat No.: ARM2058
Size：
| Product Name: | NDUFA1 Recombinant Rabbit mAb |
| Cat No.: | ARM2058 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human NDUFA1 |
| calculated molecular weight: | 8 kDa |
| observed molecular weight: | 8 kDa |
| genbank accession number: | O15239 |
| gene id (ncbi): | 4694 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MWFE; ZNF183; CI-MWFE; MC1DN12 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008] |