C3 Recombinant Rabbit mAb
Cat No.: ARM2045
Size：
| Product Name: | C3 Recombinant Rabbit mAb |
| Cat No.: | ARM2045 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,ICC/IF,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,ICC/IF,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human C3 |
| calculated molecular weight: | 187 kDa |
| observed molecular weight: | 120 kDa |
| genbank accession number: | P01024 |
| gene id (ncbi): | 718 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015] |