NXF1 Recombinant Rabbit mAb
Cat No.: ARM2040
Size：
| Product Name: | NXF1 Recombinant Rabbit mAb |
| Cat No.: | ARM2040 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human NXF1 |
| calculated molecular weight: | 70 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | Q9UBU9 |
| gene id (ncbi): | 10482 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TAP; MEX67 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |